Low-level laser irradiation stimulated the proliferation of mouse mesenchymal stem cells without causing nuclear alterations. The biostimulation of mesenchymal stem cells using laser therapy might be an important tool for regenerative therapy and tissue engineering.
https://www.ncbi.nlm.nih.gov/pubmed/26183254
Min KH, Byun JH, Heo CY, Kim EH, Choi HY, Pak CS.
This study was performed to investigate the safety and efficacy of the intra-articular infusion of ex vivo expanded autologous bone marrow-derived mesenchymal stem cells (BM-MSC) to a cohort of patients with articular cartilage defects in the hip.
https://academic.oup.com/jhps/article/4/2/159/3074996
Rodrigo Mardones, Claudio M. Jofré, L. Tobar, José J. Minguell
This review summarizes recently reported MSC-based clinical trials and discusses new research directions with particular focus on the potential application of MSC-derived extracellular vehicles, miRNAs and advanced gene editing techniques.
https://www.sciencedirect.com/science/article/pii/S2214031X17300049
Wayne Yuk-wai Lee and Bin Wang
This review examines emerging trends on using stem cells in cartilage tissue repair and regenerative medicine. It focuses on the characterization of cartilage stem cells, the chondrogenic differentiation of stem cells, and the various strategies, approaches, and clinical studies.
https://www.hindawi.com/journals/sci/2017/4130607/
Mingjie Wang, Zhiguo Yuan, Ning Ma, Chunxiang Hao, Weimin Guo, Gengyi Zou, Yu Zhang, Mingxue Chen, Shuang Gao, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Shibi Lu, Shuyun Liu, and Quanyi Guo
